Clinical Research Locators
Voluntary participation in clinical medical trials can be a means of obtaining
quality medical care for individuals who do not have health insurance or other means of affording doctors’ visits
Clinical trials are conducted to test newly developed drugs and medical devices to
determine their safety and effectiveness before they are approved for general recommended use by the public.
Research subjects are the voluntary participants on whom the new
medications or devices are tested. Healthcare professionals, usually
doctors, administering the research drugs or devices according to the clinical trial guidelines or protocol are
known as principal investigators.
In theUnited States, clinical trials must be approved by independent ethics
committees known as institutional review boards (IRBs) which monitor and review the research activity to protect
the safety and welfare of research subjects. These committees usually function at the local level and are empowered
by the Food and Drug Administration (FDA) and Department of Health and Human Services regulations to approve
and/or require modifications of a planned trial protocol prior to approval of the research or disapprove the
research. The monitory role of the IRB involves conducting regular meetings of its members and conveying
appropriate and important information of a scientific, regulatory or ethical nature to the principal investigators
involved in the respective clinical trial throughout the duration of the research activity.
To find clinical trials for varying conditions and research
sites in various geographic locations visit the following websites.
ClinicalTrials.gov provides patients, family members, and members of the public easy and free access to information on clinical studies for a wide range of diseases and conditions.
CenterWatch has one of the larges and most comprehensive global listings of industry-sponsored- and government-sponsored clinical trials on the Internet.